How Do I Create This Grid In HTML/CSS (no JS)

I have to implement this grid of divs. It won't change often, but it may at some point (meaning a box may be removed, and another resized). Each black box will eventually contain a

Solution 1:

A grid based approach would be my recommendation. Something like: http://960.gs/

EDIT (some more options)

http://developer.yahoo.com/yui/grids/

http://cssgrid.net/